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Cayman Chemical BPTES, Purity: ≥95%, CAS: 314045-39-1, 10 mg
SDP

Catalog No. 502982630
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An allosteric inhibitor of GLS1 (IC50 = 3.3 μM); selective for GLS1 over GLS2, glutamate dehydrogenase, and γ-glutamyl transpeptidase; decreases glutaminase activity and reduces proliferation of aerobic P493 cells; induces cell death, increases the production of ROS, and reduces ATP levels in hypoxic P493 cells; decreases ATP-linked and uncoupled oxygen consumption in C2C12 myotubes when used in combination with UK 5099 and/or etomoxir; reduces tumor volume in a P493 lymphoma mouse xenograft model at 12.5 mg/kg

Catalog No. 50-298-2630 Supplier Cayman Chemical Supplier No. 1928410 MG
May include imposed supplier surcharges.
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An allosteric inhibitor of GLS1 (IC50 = 3.3 μM); selective for GLS1 over GLS2, glutamate dehydrogenase, and γ-glutamyl transpeptidase; decreases glutaminase activity and reduces proliferation of aerobic P493 cells; induces cell death, increases the production of ROS, and reduces ATP levels in hypoxic P493 cells; decreases ATP-linked and uncoupled oxygen consumption in C2C12 myotubes when used in combination with UK 5099 and/or etomoxir; reduces tumor volume in a P493 lymphoma mouse xenograft model at 12.5 mg/kg

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