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Cayman Chemical C-82, Purity: ≥98%, CAS: 1422253-37-9, 1 mg
SDP

Catalog No. 502978512
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A β-catenin/CBP inhibitor and active metabolite of PRI-724; reduces the proliferation and protein levels of cyclin D1, α-smooth muscle actin (α-Sma), and Ki-67, a marker of cell proliferation, in primary mouse HSCs at 10 µM; decreases viability in continuous culture-activated primary mouse HSCs at 10 µM; induces apoptosis in non-stem- and stem cell subpopulations of tyrosine kinase inhibitor-resistant, patient-derived, and blast crisis phase CML cells with or without co-culture of primary human bone marrow MSCs in combination with nilotinib

Catalog No. 50-297-8512 Supplier Cayman Chemical Supplier No. 420381 MG
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A β-catenin/CBP inhibitor and active metabolite of PRI-724; reduces the proliferation and protein levels of cyclin D1, α-smooth muscle actin (α-Sma), and Ki-67, a marker of cell proliferation, in primary mouse HSCs at 10 µM; decreases viability in continuous culture-activated primary mouse HSCs at 10 µM; induces apoptosis in non-stem- and stem cell subpopulations of tyrosine kinase inhibitor-resistant, patient-derived, and blast crisis phase CML cells with or without co-culture of primary human bone marrow MSCs in combination with nilotinib

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