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Cayman Chemical CC-122, Purity: ≥98%, CAS: 1015474-32-4, 50 mg
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Catalog No. 502935160
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A pleiotropic pathway modifier with anticancer activity; binds to cereblon in U266 multiple myeloma cell extracts; induces recruitment and degradation of Aiolos and Ikaros in TMD8, OCI-LY10, and Karpas 422 DLBCL cells at 0.1, 1, and 10 μM; decreases proliferation and induces apoptosis ABC and GCB DLBCL cell lines from 0.1-10,000 nM; stimulates IL-2 production in mouse primary T cells; decreases tumor levels of Aiolos and Ikaros and reduces tumor growth in OCI-LY10 ABC DLBCL and WSU-DLCL2 GCB DLBCL mouse xenograft models

Catalog No. 50-293-5160 Supplier Cayman Chemical Supplier No. 2625750 MG
May include imposed supplier surcharges.
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A pleiotropic pathway modifier with anticancer activity; binds to cereblon in U266 multiple myeloma cell extracts; induces recruitment and degradation of Aiolos and Ikaros in TMD8, OCI-LY10, and Karpas 422 DLBCL cells at 0.1, 1, and 10 μM; decreases proliferation and induces apoptosis ABC and GCB DLBCL cell lines from 0.1-10,000 nM; stimulates IL-2 production in mouse primary T cells; decreases tumor levels of Aiolos and Ikaros and reduces tumor growth in OCI-LY10 ABC DLBCL and WSU-DLCL2 GCB DLBCL mouse xenograft models

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