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Cayman Chemical CDDO-Im, Purity: ≥95%, CAS: 443104-02-7, 1 mg
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Catalog No. 502992588
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An activator of Nrf2 signaling; increases the expression of Nrf2 target genes and activates HO-1 in CV-1 cells at 100 nM; binds to PPARγ and PPARα (Kis = 344 and 232 nM, respectively) and induces PPARγ transactivation in SW480 cells; inhibits NOS production in isolated mouse macrophages (IC50 = 0.014 nM); inhibits proliferation of U937 and MCF-7 cells at 300 nM; reduces fatty acid synthesis in LiSa-2 human liposarcoma cells at 100 nM; reduces tumor growth in a B16 murine melanoma model at 50 µg/animal twice per day

Catalog No. 50-299-2588 Supplier Cayman Chemical Supplier No. 317631 MG
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An activator of Nrf2 signaling; increases the expression of Nrf2 target genes and activates HO-1 in CV-1 cells at 100 nM; binds to PPARγ and PPARα (Kis = 344 and 232 nM, respectively) and induces PPARγ transactivation in SW480 cells; inhibits NOS production in isolated mouse macrophages (IC50 = 0.014 nM); inhibits proliferation of U937 and MCF-7 cells at 300 nM; reduces fatty acid synthesis in LiSa-2 human liposarcoma cells at 100 nM; reduces tumor growth in a B16 murine melanoma model at 50 µg/animal twice per day

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