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Cayman Chemical CGS 12066B, Purity: ≥98%, CAS: 109028-10-6, 25 mg
SDP

Catalog No. 502991367
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A 5-HT1B receptor agonist (IC50 = 51 nM); selective for 5-HT1B over 5-HT1A and 5-HT2 receptors (IC50s = 876 and 6,480 nM, respectively), as well as α1-, α2-, and β-adrenergic and dopamine D1 and D2 receptors (IC50s = >6,000, >1,000, >1,000, >5,000, and >5,000 nM, respectively); inhibits forskolin-induced cAMP accumulation in opossum kidney cells from 0.001-1 µM; reduces 5-HTP accumulaiton in the the fronto-parietal cortex (ED50 = 7.92 µmol/kg) and induces dorsal raphe cell firing in rats (ED50 = 358 nmol/kg); decreases interfemale and intermale aggression in Syrian hamsters

Catalog No. 50-299-1367 Supplier Cayman Chemical Supplier No. 3062325 MG
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A 5-HT1B receptor agonist (IC50 = 51 nM); selective for 5-HT1B over 5-HT1A and 5-HT2 receptors (IC50s = 876 and 6,480 nM, respectively), as well as α1-, α2-, and β-adrenergic and dopamine D1 and D2 receptors (IC50s = >6,000, >1,000, >1,000, >5,000, and >5,000 nM, respectively); inhibits forskolin-induced cAMP accumulation in opossum kidney cells from 0.001-1 µM; reduces 5-HTP accumulaiton in the the fronto-parietal cortex (ED50 = 7.92 µmol/kg) and induces dorsal raphe cell firing in rats (ED50 = 358 nmol/kg); decreases interfemale and intermale aggression in Syrian hamsters

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