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Cayman Chemical CM-272, Purity: ≥95%, CAS: 1846570-31-7, 1 mg
SDP

Catalog No. 502936356
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An inhibitor of G9a, GLP, and DNA methyltransferases (IC50s = 8, 2, 382, 85, and 1,200 nM for G9a, GLP, DNMT1, DNMT3A, and DNMT3B, respectively); inhibits the growth of, and induces apoptosis in, hematological cancer cell lines (GI50s = 218-455 nM); induces the expression of IFN-stimulated genes and immunologic cell death markers in hematological cancer cell lines; reduces tumor growth in MV4-11 and EGI-1 mouse xenograft models at 2.5 mg/kg; increases survival in CEMO-1 and RT112 mouse xenograft models at 2.5 and 5 mg/kg, respectively

Catalog No. 50-293-6356 Supplier Cayman Chemical Supplier No. 259481 MG
May include imposed supplier surcharges.
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An inhibitor of G9a, GLP, and DNA methyltransferases (IC50s = 8, 2, 382, 85, and 1,200 nM for G9a, GLP, DNMT1, DNMT3A, and DNMT3B, respectively); inhibits the growth of, and induces apoptosis in, hematological cancer cell lines (GI50s = 218-455 nM); induces the expression of IFN-stimulated genes and immunologic cell death markers in hematological cancer cell lines; reduces tumor growth in MV4-11 and EGI-1 mouse xenograft models at 2.5 mg/kg; increases survival in CEMO-1 and RT112 mouse xenograft models at 2.5 and 5 mg/kg, respectively

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