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Cayman Chemical CPYPP, Purity: ≥98% (mixture of isomers), CAS: 310460-39-0, 50 mg
SDP

Catalog No. 502979637
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An inhibitor of DOCK2 (IC50 = 22.8 µM for its GEF activity), DOCK5, and DOCK180; selective for these DOCKs over DOCK9; prevents chemokine-induced Rac activation in T and B cells at 100 µM; reduces migration of T cells to peripheral lymph nodes in mice at 5 mg/animal following adoptive transfer of spleen cells from knock-in mice expressing GFP-tagged DOCK2; reduces MPO activity in lung tissue, LPS-induced cytokine release in serum, and lung injury severity in a mouse model of endotoxemia-induced acute lung injury at 250 mg/kg

Catalog No. 50-297-9637 Supplier Cayman Chemical Supplier No. 1738650 MG
May include imposed supplier surcharges.
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An inhibitor of DOCK2 (IC50 = 22.8 µM for its GEF activity), DOCK5, and DOCK180; selective for these DOCKs over DOCK9; prevents chemokine-induced Rac activation in T and B cells at 100 µM; reduces migration of T cells to peripheral lymph nodes in mice at 5 mg/animal following adoptive transfer of spleen cells from knock-in mice expressing GFP-tagged DOCK2; reduces MPO activity in lung tissue, LPS-induced cytokine release in serum, and lung injury severity in a mouse model of endotoxemia-induced acute lung injury at 250 mg/kg

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