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Cayman Chemical ANTIBODY d-3032 10mg

Supplier: Cayman Chemical 4183810 MG
An inhibitor of the MDM2-p53 protein-protein interaction; induces apoptosis in WaGa and PeTa cells at 100 nM; decreases the viability of p53 wild-type MKL-1 cells but not p53 knockout MLK-1 cells at 1 µM; reduces tumor volume and increases survival in a PDX mouse model of Merkel cell carcinoma at 100 mg/kg per day
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