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Cayman Chemical dBET6, Purity: ≥98%, CAS: 1950634-92-0, 10 mg
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Catalog No. 502913638
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A PROTAC that drives BRD4 degradation; binds to BRD4 (IC50 = 14 nM) and induces its degradation at 100 nM, leading to a global inhibition of transcription in MOLT-4 cells; reduces leukemic burden in a MOLT-4 T-ALL mouse xenograft model when administered at a dose of 7.5 mg/kg twice per day

Catalog No. 50-291-3638 Supplier Cayman Chemical Supplier No. 3538510 MG
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A PROTAC that drives BRD4 degradation; binds to BRD4 (IC50 = 14 nM) and induces its degradation at 100 nM, leading to a global inhibition of transcription in MOLT-4 cells; reduces leukemic burden in a MOLT-4 T-ALL mouse xenograft model when administered at a dose of 7.5 mg/kg twice per day

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