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Cayman Chemical Defactinib, Purity: ≥95%, CAS: 1073154-85-4, 5 mg
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Catalog No. 502980091
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A dose-dependent inhibitor of FAK, with maximal inhibition of FAK autophosphorylation in cells achieved at 10 µM; restores the chemosensitivity of taxane-resistant cells to paclitaxel; orally bioavailable, inhibiting FAK and augmenting paclitaxel action against ovarian cancer cell tumors in mice

Catalog No. 50-298-0091 Supplier Cayman Chemical Supplier No. 177375 MG
May include imposed supplier surcharges.
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A dose-dependent inhibitor of FAK, with maximal inhibition of FAK autophosphorylation in cells achieved at 10 µM; restores the chemosensitivity of taxane-resistant cells to paclitaxel; orally bioavailable, inhibiting FAK and augmenting paclitaxel action against ovarian cancer cell tumors in mice

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