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Cayman Chemical EHop-016, Purity: ≥98%, CAS: 1380432-32-5, 10 mg
SDP

Catalog No. 502964224
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A Rac1 and Rac3 inhibitor; inhibits Rac1 activity (IC50 = 1.1 μM); inhibits Rac3 activity (58% at 1 μM); inhibits Cdc42 activity (28% at ≥ 5 μM); increases RhoA activity (1.3-fold at ≥2 μM); increases Rac-regulated lamellipodia formation and PAK1-mediated cell migration in MDA-MB-435 cells (2-4 μM); lowers mammary fat pad tumor growth, metastasis, and angiogenesis in a nude mouse model of breast cancer (25 mg/kg); inhibits mutant KIT-induced growth in systemic mastocytosis and AML cells (≥2.5 μM)

Catalog No. 50-296-4224 Supplier Cayman Chemical Supplier No. 2155710 MG
May include imposed supplier surcharges.
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A Rac1 and Rac3 inhibitor; inhibits Rac1 activity (IC50 = 1.1 μM); inhibits Rac3 activity (58% at 1 μM); inhibits Cdc42 activity (28% at ≥ 5 μM); increases RhoA activity (1.3-fold at ≥2 μM); increases Rac-regulated lamellipodia formation and PAK1-mediated cell migration in MDA-MB-435 cells (2-4 μM); lowers mammary fat pad tumor growth, metastasis, and angiogenesis in a nude mouse model of breast cancer (25 mg/kg); inhibits mutant KIT-induced growth in systemic mastocytosis and AML cells (≥2.5 μM)

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