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Cayman Chemical X-376, Purity: ≥98%, CAS: 1365267-27-1, 25 mg
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Catalog No. 502980896
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An ALK and MET inhibitor (IC50s = 0.61 and 0.69 nM, respectively); selectively inhibits the growth of cancer cell lines harboring gain-of-function ALK-fusion proteins (IC50s = 32-150 nM) over those with cell growth driven by other mutant kinases (IC50s = 1,427->3,000 nM); reduces tumor growth in an NCI H3122 lung cancer mouse xenograft model at 50 mg/kg

Catalog No. 50-298-0896 Supplier Cayman Chemical Supplier No. 2134125 MG
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An ALK and MET inhibitor (IC50s = 0.61 and 0.69 nM, respectively); selectively inhibits the growth of cancer cell lines harboring gain-of-function ALK-fusion proteins (IC50s = 32-150 nM) over those with cell growth driven by other mutant kinases (IC50s = 1,427->3,000 nM); reduces tumor growth in an NCI H3122 lung cancer mouse xenograft model at 50 mg/kg

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