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Cayman Chemical ETC-1002, Purity: ≥95%, CAS: 738606-46-7, 5 mg
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Catalog No. 502933759
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A prodrug form of ETC-1002-CoA; conjugated to CoA by ACSVL1 to form ETC-1002-CoA, which inhibits ATP citrate lyase (Ki = 2 μM) and activates AMPK; suppresses total lipid synthesis in wild-type and AMPKβ1 knockout primary murine hepatocytes; prevents increases in hepatic cholesterol and reduces the size of aortic atherosclerotic lesions induced by a high-fat high-cholesterol diet in DKO mice

Catalog No. 50-293-3759 Supplier Cayman Chemical Supplier No. 264095 MG
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A prodrug form of ETC-1002-CoA; conjugated to CoA by ACSVL1 to form ETC-1002-CoA, which inhibits ATP citrate lyase (Ki = 2 μM) and activates AMPK; suppresses total lipid synthesis in wild-type and AMPKβ1 knockout primary murine hepatocytes; prevents increases in hepatic cholesterol and reduces the size of aortic atherosclerotic lesions induced by a high-fat high-cholesterol diet in DKO mice

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