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Cayman Chemical Fidarestat, Purity: ≥95%, CAS: 136087-85-9, 10 mg
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Catalog No. 502987363
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An aldose reductase inhibitor (IC50 = 0.026 μM); inhibits AKR1B10 (IC50 = 33 μM); decreases sorbitol and myo-inositol levels in the sciatic nerves of STZ-induced diabetic rats (2 mg/kg per day); decreases nerve fiber abnormalities and reverses slowing of MNCV in an STZ-induced diabetic rat model of peripheral neuropathy (2 mg/kg per day); decreases the pain threshold in STZ-induced diabetic mice overexpressing human aldose reductase (4 mg/kg per day); decreases metastasis in a KM20 human colorectal cancer mouse xenograft model (50 mg/kg per day)

Catalog No. 50-298-7363 Supplier Cayman Chemical Supplier No. 2175610 MG
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An aldose reductase inhibitor (IC50 = 0.026 μM); inhibits AKR1B10 (IC50 = 33 μM); decreases sorbitol and myo-inositol levels in the sciatic nerves of STZ-induced diabetic rats (2 mg/kg per day); decreases nerve fiber abnormalities and reverses slowing of MNCV in an STZ-induced diabetic rat model of peripheral neuropathy (2 mg/kg per day); decreases the pain threshold in STZ-induced diabetic mice overexpressing human aldose reductase (4 mg/kg per day); decreases metastasis in a KM20 human colorectal cancer mouse xenograft model (50 mg/kg per day)

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