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Cayman Chemical FX1, Purity: ≥95%, CAS: 1426138-42-2, 10 mg
SDP

Catalog No. 502994345
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A BCL6 inhibitor (IC50 = ~35 μM); selective for BCL6 over a panel of 50 kinases at 10 μM; reduces recruitment of the BCL6 corepressor proteins SMRT and BCOR to the BCL6 target loci CDKN1A, CD69, and CXCR4 in a ChIP assay at 50 μM; represses growth of Farage, SU-DLH-6, DOHH-2, OCI-Ly7, RCK8, SU-DHL-4, OCI-Ly1, and SC-1 BCL6-dependent cell lines (GI50s = 16-54 μM); reduces tumor volume in an HBL-1 large B cell lymphoma mouse xenograft model at 50 mg/kg

Catalog No. 50-299-4345 Supplier Cayman Chemical Supplier No. 2390810 MG
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A BCL6 inhibitor (IC50 = ~35 μM); selective for BCL6 over a panel of 50 kinases at 10 μM; reduces recruitment of the BCL6 corepressor proteins SMRT and BCOR to the BCL6 target loci CDKN1A, CD69, and CXCR4 in a ChIP assay at 50 μM; represses growth of Farage, SU-DLH-6, DOHH-2, OCI-Ly7, RCK8, SU-DHL-4, OCI-Ly1, and SC-1 BCL6-dependent cell lines (GI50s = 16-54 μM); reduces tumor volume in an HBL-1 large B cell lymphoma mouse xenograft model at 50 mg/kg

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