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Cayman Chemical GDC-1971, Purity: ≥98%, CAS: 2377352-49-1, 5 mg
SDP

Catalog No. 502943098
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An SHP-2 inhibitor (IC50 = E76K (IC50 = 0.17 µM); reduces the levels of phosphorylated ERK in a reporter assay using KYSE-520 cancer cells (IC90 = 0.012 µM) and inhibits proliferation of the same cells (IC50 = 0.32 µM); reduces tumor volume in KYSE-520 and NCI H358 mouse xenograft models at 30 or 100 mg/kg two times per day

Catalog No. 50-294-3098 Supplier Cayman Chemical Supplier No. 398845 MG
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An SHP-2 inhibitor (IC50 = E76K (IC50 = 0.17 µM); reduces the levels of phosphorylated ERK in a reporter assay using KYSE-520 cancer cells (IC90 = 0.012 µM) and inhibits proliferation of the same cells (IC50 = 0.32 µM); reduces tumor volume in KYSE-520 and NCI H358 mouse xenograft models at 30 or 100 mg/kg two times per day

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