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Cayman Chemical GW 280264X, Purity: ≥95%, CAS: 866924-39-2, 10 mg
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Catalog No. 502990942
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An ADAM17/TACE and ADAM10 inhibitor (IC50s = 8 and 11.5 nM, respectively); inhibits TNF-α-induced cleavage of endomucin in HUVECs at 10 µM; inhibits PMA-induced ACE2 ectodomain shedding in HEK-ACE2 cells at 1 and 10 µM; reduces ACE2 shedding and prevents SARS-CoV-2 infection in HK-2 cell

Catalog No. 50-299-0942 Supplier Cayman Chemical Supplier No. 3138810 MG
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An ADAM17/TACE and ADAM10 inhibitor (IC50s = 8 and 11.5 nM, respectively); inhibits TNF-α-induced cleavage of endomucin in HUVECs at 10 µM; inhibits PMA-induced ACE2 ectodomain shedding in HEK-ACE2 cells at 1 and 10 µM; reduces ACE2 shedding and prevents SARS-CoV-2 infection in HK-2 cell

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