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Cayman Chemical HM30181, Purity: ≥98%, CAS: 849675-66-7, 10 mg
SDP

Catalog No. 502946240
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A P-gp inhibitor (IC50 = 0.63 nM); selective for P-gp over BCRP (IC50 = 3,700 nM), as well as MRP1, MRP2, and MRP3 at 100 µM; inhibits transepithelial basal-to-apical transport of paclitaxel in MDCK monolayers overexpressing P-gp (IC50 = 35.4 nM); inhibits tumor growth and induces tumor regression in an HT-29 mouse xenograft model at 10 and 20 mg/kg, respectively, in combination with paclitaxel

Catalog No. 50-294-6240 Supplier Cayman Chemical Supplier No. 3287310 MG
May include imposed supplier surcharges.
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A P-gp inhibitor (IC50 = 0.63 nM); selective for P-gp over BCRP (IC50 = 3,700 nM), as well as MRP1, MRP2, and MRP3 at 100 µM; inhibits transepithelial basal-to-apical transport of paclitaxel in MDCK monolayers overexpressing P-gp (IC50 = 35.4 nM); inhibits tumor growth and induces tumor regression in an HT-29 mouse xenograft model at 10 and 20 mg/kg, respectively, in combination with paclitaxel

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