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Cayman Chemical ANTIBODY HWL-088 5mg

Supplier: Cayman Chemical 302275 MG
An agonist of FFAR1/GPR40 and PPARδ; induces calcium mobilization in CHO cells expressing FFAR1/GPR40 (EC50 = 18.9 nM) and transactivation of PPARδ in a reporter assay using HEK293 cells (EC50 = 570.9 nM); selective for FFAR1/GPR40 and PPARδ over PPARα and PPARγ; decreases plasma glucose, HbA1c, total cholesterol, triglyceride, and LDL levels, increases plasma insulin levels, and reduces hepatic lipid accumulation in ob/ob mice at 40 mg/kg
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