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Cayman Chemical KDU691, Purity: ≥98%, CAS: 1513879-19-0, 10 mg
SDP

Catalog No. 502940120
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An antimalarial compound; inhibits the activity of recombinant P. vivax PI4K (IC50 = 1.5 nM); selective for P. vivax PI4K over recombinant human PI4KβIII and PI3Kα, -β, -ɣ, and -δ (IC50s = 7.9, 8.8, 2.4, 8, and 3.4 µM, respectively), as well as VPS34 (IC50 = >9.7 µM) and 36 additional kinases in a panel of lipid and protein kinases (IC50s = >10 µM); active against P. falciparum and P. yoelii schizonts (IC50s = 0.06 and 0.04 µM, respectively), as well as P. cynomolgi schizonts and hypnozoites (IC50s = 0.11 and 0.2 µM, respectively); completely prevents, but does not eradicate established, P. cynomolgi infection in rhesus monkeys at 20 mg/kg

Catalog No. 50-294-0120 Supplier Cayman Chemical Supplier No. 2901910 MG
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An antimalarial compound; inhibits the activity of recombinant P. vivax PI4K (IC50 = 1.5 nM); selective for P. vivax PI4K over recombinant human PI4KβIII and PI3Kα, -β, -ɣ, and -δ (IC50s = 7.9, 8.8, 2.4, 8, and 3.4 µM, respectively), as well as VPS34 (IC50 = >9.7 µM) and 36 additional kinases in a panel of lipid and protein kinases (IC50s = >10 µM); active against P. falciparum and P. yoelii schizonts (IC50s = 0.06 and 0.04 µM, respectively), as well as P. cynomolgi schizonts and hypnozoites (IC50s = 0.11 and 0.2 µM, respectively); completely prevents, but does not eradicate established, P. cynomolgi infection in rhesus monkeys at 20 mg/kg

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