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Cayman Chemical ANTIBODY KI-696 10mg
SDP

Supplier:  Cayman Chemical 4203910 MG

Encompass_Preferred

An inhibitor of FLAP (IC50 1.6 nM for the human enzyme) inhibits LTB4 biosynthesis in A23187-stimulated isolated rat neutrophils (IC50 6 nM) but does not inhibit 5-LO in a cell-free assay (IC50 4 UM for the rat enzyme) prevents increases in airway resistance and decreases in dynamic compliance in Ascaris antigen-induced squirrel monkeys at 0.3 and 1 mg/kg decreases proteinuria and reduces decreases in renal LTC4 synthase activity in a rat model of nephrotoxic rabbit serum-induced glomerulonephritis at 60 mg/kg induces apoptosis in LNCaP cells at 8 UM

Catalog No. 50-294-5661


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