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Cayman Chemical KLH45, Purity: ≥98%, CAS: 1632236-44-2, 5 mg
SDP

Catalog No. 502981655
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An inhibitor of DDHD2 (IC50 = 1.3 nM); selective for DDHD2 over greater than 50 serine hydrolases, including DDHD1 and Sec23ip, but does inhibit ABHD6; inhibits DDHD2 and ABHD6 in Neuro2A cells at 95% at 25 nM; prevents increases in TAG hydrolase activity in HEK293T cell lysates expressing DDHD2 and incubated with a radiolabeled TAG substrate at 2 µM; decreases TAG levels in mouse CNS at 20 mg/kg twice per day for four days; reverses DDHD2-induced lipid droplet reduction in COS-7 cells expressing species recombinant DDHD2 and loaded with oleic acid at 2 µM

Catalog No. 50-298-1655 Supplier Cayman Chemical Supplier No. 198895 MG
May include imposed supplier surcharges.
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An inhibitor of DDHD2 (IC50 = 1.3 nM); selective for DDHD2 over greater than 50 serine hydrolases, including DDHD1 and Sec23ip, but does inhibit ABHD6; inhibits DDHD2 and ABHD6 in Neuro2A cells at 95% at 25 nM; prevents increases in TAG hydrolase activity in HEK293T cell lysates expressing DDHD2 and incubated with a radiolabeled TAG substrate at 2 µM; decreases TAG levels in mouse CNS at 20 mg/kg twice per day for four days; reverses DDHD2-induced lipid droplet reduction in COS-7 cells expressing species recombinant DDHD2 and loaded with oleic acid at 2 µM

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