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Cayman Chemical MC70, Purity: ≥98%, CAS: 1031367-64-2, 10 mg
SDP

Catalog No. 502981373
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A P-gp inhibitor; inhibits the efflux of [3H]vinblastine by ABCB1 in Caco-2 colon cancer cells (EC50 = 0.05 µM); inhibits the efflux of rhodamine-123 and calcein-AM by BCRP and MRP1 in MDCK cells (EC50s = 73 and 9.3 µM, respectively); enhances growth inhibition of MCF-7/ADR breast cancer cells at 2 or 20 µM when used in combination with doxorubicin in vitro, but does not alter the effectiveness of doxorubicin on growth inhibition in Caco-2 cells; increases phosphorylation of p38 and JNK in Caco-2 cells and MCF-7/ADR cells when used at a concentration of 20 µM

Catalog No. 50-298-1373 Supplier Cayman Chemical Supplier No. 2133010 MG
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A P-gp inhibitor; inhibits the efflux of [3H]vinblastine by ABCB1 in Caco-2 colon cancer cells (EC50 = 0.05 µM); inhibits the efflux of rhodamine-123 and calcein-AM by BCRP and MRP1 in MDCK cells (EC50s = 73 and 9.3 µM, respectively); enhances growth inhibition of MCF-7/ADR breast cancer cells at 2 or 20 µM when used in combination with doxorubicin in vitro, but does not alter the effectiveness of doxorubicin on growth inhibition in Caco-2 cells; increases phosphorylation of p38 and JNK in Caco-2 cells and MCF-7/ADR cells when used at a concentration of 20 µM

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