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Cayman Chemical MF766, Purity: ≥95%, CAS: 1050656-06-8, 25 mg
SDP

Catalog No. 502911665
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An EP4 receptor antagonist (Ki = 0.23 nM); selective for EP4 over DP1 (Ki = 1,648 nM) as well as EP1, EP2, EP3, CRTH2/DP2, IP, TP, and FP recetors (Kis = >6,000 nM for all); inhibits PGE2-induced cAMP accumulation in HEK293 cells (IC50 = 1.3 nM); reverses PGE2-induced decreases in IFN-γ production in IL-2-stimulated primary human natural killer cells at 312.5 and 1,250 nM; reduces paw edema in a rat model of adjuvant-induced arthritis; inhibits tumor growth in a CT26 murine colon cancer model at 30 mg/kg

Catalog No. 50-291-1665 Supplier Cayman Chemical Supplier No. 3607625 MG
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An EP4 receptor antagonist (Ki = 0.23 nM); selective for EP4 over DP1 (Ki = 1,648 nM) as well as EP1, EP2, EP3, CRTH2/DP2, IP, TP, and FP recetors (Kis = >6,000 nM for all); inhibits PGE2-induced cAMP accumulation in HEK293 cells (IC50 = 1.3 nM); reverses PGE2-induced decreases in IFN-γ production in IL-2-stimulated primary human natural killer cells at 312.5 and 1,250 nM; reduces paw edema in a rat model of adjuvant-induced arthritis; inhibits tumor growth in a CT26 murine colon cancer model at 30 mg/kg

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