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Cayman Chemical ANTIBODY MK-8745 25mg
Supplier: Cayman Chemical 2619025 MG
An Aurora A kinase inhibitor (IC50 = 0.6 nM); selective for Aurora A over Aurora B kinase (IC50 = 280 nM); induces cell cycle arrest at the G2/M phase in non-Hodgkin lymphoma cells at 1 μM; induces apoptosis and polyploidy in p53-positive and -negative HCT116 colon cancer cells, respectively, at 5 μM; induces apoptosis in sarcoma, melanoma, and pancreatic cancer cell lines in a p53-dependent manner at 5 μM
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