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Cayman Chemical MLN8054, Purity: ≥98%, CAS: 869363-13-3, 1 mg
SDP

Catalog No. 502937331
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An inhibitor of Aurora A kinase (IC50 = 4 nM); selective for Aurora A over Aurora B, PKC, CaMKII, Cdk2E, CK2, LCK, PKA, Chk1, Chk2, Cdk1, and Plk1 (IC50s = 0.172-100 µM); induces cell cycle arrest at the G2/M phase and the formation of abnormal mitotic spindles in HCT116 colorectal and PC3 prostate cancer cells; inhibits the growth of various cancer cells (IC50s = 0.11-1.43 µM); reduces tumor volume in HCT116 and PC3 mouse xenograft models at 30 mg/kg

Catalog No. 50-293-7331 Supplier Cayman Chemical Supplier No. 273401 MG
May include imposed supplier surcharges.
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An inhibitor of Aurora A kinase (IC50 = 4 nM); selective for Aurora A over Aurora B, PKC, CaMKII, Cdk2E, CK2, LCK, PKA, Chk1, Chk2, Cdk1, and Plk1 (IC50s = 0.172-100 µM); induces cell cycle arrest at the G2/M phase and the formation of abnormal mitotic spindles in HCT116 colorectal and PC3 prostate cancer cells; inhibits the growth of various cancer cells (IC50s = 0.11-1.43 µM); reduces tumor volume in HCT116 and PC3 mouse xenograft models at 30 mg/kg

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