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Cayman Chemical Motolimod, Purity: ≥98%, CAS: 926927-61-9, 5 mg
SDP

Catalog No. 502964481
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A TLR8 agonist; increases the production of TNF-α and IL-12 in human PBMCs (EC50s = 140 and 120 nM, respectively), monocytes, and dendritic cells; increases cytolysis in K562 NK cell-sensitive leukemia cells at 167 and 500 nM for 48 hours; increases plasma levels of a group of human cytokines , including IL-6, IL-12p70, TNF-α, MCP-1, and MIP-1β, in NSG-HIS mice at 1.5 and 15 mg/m2; reduces tumor growth and increases tumor infiltration of monocytes and T cells in an ovarian cancer NSG-HIS mouse model

Catalog No. 50-296-4481 Supplier Cayman Chemical Supplier No. 229525 MG
May include imposed supplier surcharges.
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A TLR8 agonist; increases the production of TNF-α and IL-12 in human PBMCs (EC50s = 140 and 120 nM, respectively), monocytes, and dendritic cells; increases cytolysis in K562 NK cell-sensitive leukemia cells at 167 and 500 nM for 48 hours; increases plasma levels of a group of human cytokines , including IL-6, IL-12p70, TNF-α, MCP-1, and MIP-1β, in NSG-HIS mice at 1.5 and 15 mg/m2; reduces tumor growth and increases tumor infiltration of monocytes and T cells in an ovarian cancer NSG-HIS mouse model

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