Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502967601

Cayman Chemical ANTIBODY NVP-BEP800 500ug
SDP

Catalog No. 502967601
Encompass_Preferred

An Hsp90 inhibitor (IC50 = 58 nM for recombinant human Hsp90β); selective for Hsp90 over GRP94 and TRAP1 (IC50s = 4.1 and 5.5 µM, respectively); inhibits the growth of BT474, SK-BR-3, MCF-7, MDA-MB-157, MDA-MB-231, MDA-MB-468, and BT-20 breast cancer cells (GI50s = 53, 56, 118, 89, 190 173, and 162 nM, respectively); reduces levels of HER2 and Raf-1 in MCF-7 cells; induces apoptosis and attenuates X-ray-induced increases in Hsp70 levels in T98G glioblastoma cells; reduces tumor volume in A375 melanoma and BT474 breast cancer mouse xenograft models from 15-50 mg/kg; reduces tumor volume in an L1T2 Kaposi sarcoma mouse xenograft model

Catalog No. 50-296-7601 Supplier Cayman Chemical Supplier No. 18383500 UG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

An Hsp90 inhibitor (IC50 = 58 nM for recombinant human Hsp90β); selective for Hsp90 over GRP94 and TRAP1 (IC50s = 4.1 and 5.5 µM, respectively); inhibits the growth of BT474, SK-BR-3, MCF-7, MDA-MB-157, MDA-MB-231, MDA-MB-468, and BT-20 breast cancer cells (GI50s = 53, 56, 118, 89, 190 173, and 162 nM, respectively); reduces levels of HER2 and Raf-1 in MCF-7 cells; induces apoptosis and attenuates X-ray-induced increases in Hsp70 levels in T98G glioblastoma cells; reduces tumor volume in A375 melanoma and BT474 breast cancer mouse xenograft models from 15-50 mg/kg; reduces tumor volume in an L1T2 Kaposi sarcoma mouse xenograft model

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.