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Cayman Chemical Oridonin, Purity: ≥98%, CAS: 28957-04-2, 5 mg
SDP

Catalog No. 502936372
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A diterpenoid with diverse biological activities; binds to β-arrestin-1 and -2 (Kds = 362 and 563 nM, respectively); inhibits β-arrestin recruitment and receptor desensitization and internalization of various GPCRs; selective for β-arrestin over Gαs, Gαq, Gα12, and Gi; inhibits Akt1 and Akt2 (IC50s = 8.4 and 8.9 µM, respectively); has anticancer activity in vitro and in a PDX mouse model; inhibits NLRP3 inflammasome assembly and activation; has anti-inflammatory activity in a mouse model of high-fat diet-induced type 2 diabetes

Catalog No. 50-293-6372 Supplier Cayman Chemical Supplier No. 256655 MG
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A diterpenoid with diverse biological activities; binds to β-arrestin-1 and -2 (Kds = 362 and 563 nM, respectively); inhibits β-arrestin recruitment and receptor desensitization and internalization of various GPCRs; selective for β-arrestin over Gαs, Gαq, Gα12, and Gi; inhibits Akt1 and Akt2 (IC50s = 8.4 and 8.9 µM, respectively); has anticancer activity in vitro and in a PDX mouse model; inhibits NLRP3 inflammasome assembly and activation; has anti-inflammatory activity in a mouse model of high-fat diet-induced type 2 diabetes

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