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Cayman Chemical PQ401, Purity: ≥98%, CAS: 196868-63-0, 10 mg
SDP

Catalog No. 502983677
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An inhibitor of IGF-1R; inhibits autophosphorylation of the recombinant IGF-1R kinase domain (IC50 = 50 = 12 μM); reduces cell viability of U87MG glioma cells (IC50 = 5 μM) and induces apoptosis and inhibits cell migration in a concentration-dependent manner; inhibits IGF-1-stimulated proliferation of MCF-7 cells in vitro (IC50 = 6 μM) and reduces tumor growth in an MCNeuA model of murine breast cancer at 50 and 100 mg/kg; has antimalarial activity against P. falciparum strain 3D7 (EC50 = 53 nM)

Catalog No. 50-298-3677 Supplier Cayman Chemical Supplier No. 2097910 MG
May include imposed supplier surcharges.
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An inhibitor of IGF-1R; inhibits autophosphorylation of the recombinant IGF-1R kinase domain (IC50 = 50 = 12 μM); reduces cell viability of U87MG glioma cells (IC50 = 5 μM) and induces apoptosis and inhibits cell migration in a concentration-dependent manner; inhibits IGF-1-stimulated proliferation of MCF-7 cells in vitro (IC50 = 6 μM) and reduces tumor growth in an MCNeuA model of murine breast cancer at 50 and 100 mg/kg; has antimalarial activity against P. falciparum strain 3D7 (EC50 = 53 nM)

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