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Cayman Chemical PRT060318, Purity: ≥98%, CAS: 1194961-19-7, 5 mg
SDP

Catalog No. 502986467
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A potent and selective Syk inhibitor (IC50 = 4 nM); inhibits 92% of Syk activity, while other kinases retain >70% activity, at a concentration of 50 nM in a panel of 270 kinases; inhibits convulxin-induced aggregation of human platelet-rich plasma (IC50 = 2.5 μM); prevents thrombosis in a transgenic mouse model of heparin-induced thrombocytopenia; induces CLL B cell apoptosis and inhibits the secretion of chemokines CCL3, CCL4, and CXCL13; inhibits CLL B cell chemotaxis and pseudoemperipolesis

Catalog No. 50-298-6467 Supplier Cayman Chemical Supplier No. 224765 MG
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A potent and selective Syk inhibitor (IC50 = 4 nM); inhibits 92% of Syk activity, while other kinases retain >70% activity, at a concentration of 50 nM in a panel of 270 kinases; inhibits convulxin-induced aggregation of human platelet-rich plasma (IC50 = 2.5 μM); prevents thrombosis in a transgenic mouse model of heparin-induced thrombocytopenia; induces CLL B cell apoptosis and inhibits the secretion of chemokines CCL3, CCL4, and CXCL13; inhibits CLL B cell chemotaxis and pseudoemperipolesis

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