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Cayman Chemical S-72, Purity: ≥98%, CAS: 2446799-14-8, 50 mg
SDP

Catalog No. 502918693
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An inhibitor of microtubule polymerization; inhibits microtubule polymerization in a cell-free assay at 1, 3, and 10 µM; reduces viability in MCF-7 and paclitaxel-resistant MCF-7/T cells (IC50s = 15.64 and 26.32 nM, respectively); inhibits migration and invasion, as well as the percentage of wound closure in a scratch assay in MCF-7 and MCF-7/T cells at 50 nM; induces cell cycle arrest at the G2/M phase in MCF-7/T cells and induces apoptosis in those same cells at 100 nM; inhibits STING activation in MCF-7/T cells at 100 nM; inhibits tumor growth in MCF-7/T and MX-1/T mouse xenograft models of paclitaxel-resistant breast cancer at 15 mg/kg per day

Catalog No. 50-291-8693 Supplier Cayman Chemical Supplier No. 3908350 MG
May include imposed supplier surcharges.
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An inhibitor of microtubule polymerization; inhibits microtubule polymerization in a cell-free assay at 1, 3, and 10 µM; reduces viability in MCF-7 and paclitaxel-resistant MCF-7/T cells (IC50s = 15.64 and 26.32 nM, respectively); inhibits migration and invasion, as well as the percentage of wound closure in a scratch assay in MCF-7 and MCF-7/T cells at 50 nM; induces cell cycle arrest at the G2/M phase in MCF-7/T cells and induces apoptosis in those same cells at 100 nM; inhibits STING activation in MCF-7/T cells at 100 nM; inhibits tumor growth in MCF-7/T and MX-1/T mouse xenograft models of paclitaxel-resistant breast cancer at 15 mg/kg per day

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