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Cayman Chemical SAG 21k, Purity: ≥98%, CAS: 946002-48-8, 10 mg
SDP

Catalog No. 502944077
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An agonist of the hedgehog signaling pathway; activates Smo in a reporter assay using C3H/10T1/2 cells expressing Smo (EC50 = 0.3 nM); increases the levels of mRNA encoding Ki67, Ccdc1, collagen II, ALP, Gli1, and Gli2 and decreases the levels of mRNA encoding MMP-13 in mouse primary chondrocytes at 1 nM; induces the formation of bone calluses and partial bone unions and increases total bone volume, but not total tissue volume, in a mouse model of surgery-induced non-healing bone fracture at 5 mg/kg per day

Catalog No. 50-294-4077 Supplier Cayman Chemical Supplier No. 4112110 MG
May include imposed supplier surcharges.
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An agonist of the hedgehog signaling pathway; activates Smo in a reporter assay using C3H/10T1/2 cells expressing Smo (EC50 = 0.3 nM); increases the levels of mRNA encoding Ki67, Ccdc1, collagen II, ALP, Gli1, and Gli2 and decreases the levels of mRNA encoding MMP-13 in mouse primary chondrocytes at 1 nM; induces the formation of bone calluses and partial bone unions and increases total bone volume, but not total tissue volume, in a mouse model of surgery-induced non-healing bone fracture at 5 mg/kg per day

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