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Cayman Chemical ANTIBODY SGC3027 1mg
SDP

Supplier:  Cayman Chemical 253251 MG

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An allosteric agonist of a7 subunit-containing nAChRs activates human a7 subunit-containing nAChRs expressed in X. laevis oocytes more potently than acetylcholine (EC50s 17 and 128 UM respectively) selective for a7 subunit-containing nAChRs having no activity for a1B1ε- a3B4- and a4B2 subunit-containing nAChRs at 100 UM potentiates acetylcholine-induced activation of a7 subunit-containing nAChRs by greater than 540-fold in X. laevis oocytes at 10 UM activates wild-type a7 subunit-containing nAChRs and nAChRs containing the a7 subunit and W148F but not M253L mutations in X. laevis oocytes

Catalog No. 50-293-2661


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