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Cayman Chemical SJB2-043, Purity: ≥98%, CAS: 63388-44-3, 25 mg
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Catalog No. 502914029
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An inhibitor of the USP1-UAF complex (IC50 = 0.544 µM for its deubiquitinase activity) and SARS-CoV-2 PLpro (IC50s = 0.56 and 0.091 µM using Z-LRGG-AMC or Ub-AMC, respectively, as PLpro substrates); reduces the levels of USP1, ID-1, ID-2, and ID-3 in K562 cells at 0.5-10 µM; decreases the viability of K562 cells (EC50 = 1.07 µM); induces apoptosis in K562 cells in a concentration-dependent manner

Catalog No. 50-291-4029 Supplier Cayman Chemical Supplier No. 3660525 MG
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An inhibitor of the USP1-UAF complex (IC50 = 0.544 µM for its deubiquitinase activity) and SARS-CoV-2 PLpro (IC50s = 0.56 and 0.091 µM using Z-LRGG-AMC or Ub-AMC, respectively, as PLpro substrates); reduces the levels of USP1, ID-1, ID-2, and ID-3 in K562 cells at 0.5-10 µM; decreases the viability of K562 cells (EC50 = 1.07 µM); induces apoptosis in K562 cells in a concentration-dependent manner

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