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Cayman Chemical ANTIBODY SM-164 500ug
SDP

Catalog No. 502937440
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A cell-permeable Smac mimetic and an inhibitor of XIAP; binds to BIR2 and BIR3 domain-containing XIAP (IC50 = 1.39 nM); inhibits growth (IC50 = 1 nM), as well as activates caspase-3 and caspase-9, and induces cleavage of PARP in HL-60 leukemia cells at 10 nM; reduces tumor volume by 80% in a 2LMP breast cancer mouse xenograft model at 5 mg/kg in combination with TRAIL

Catalog No. 50-293-7440 Supplier Cayman Chemical Supplier No. 28632500 UG
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A cell-permeable Smac mimetic and an inhibitor of XIAP; binds to BIR2 and BIR3 domain-containing XIAP (IC50 = 1.39 nM); inhibits growth (IC50 = 1 nM), as well as activates caspase-3 and caspase-9, and induces cleavage of PARP in HL-60 leukemia cells at 10 nM; reduces tumor volume by 80% in a 2LMP breast cancer mouse xenograft model at 5 mg/kg in combination with TRAIL

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