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Cayman Chemical SM-324405, Purity: ≥95%, CAS: 677773-91-0, 10 mg
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Catalog No. 502989067
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A TLR7 agonist (EC50 = 50.1 nM in a reporter assay using HEK293 cells expressing the human receptor); selective for TLR7 over TLR8 (EC50 = >10 µM); induces IFN production in isolated human PBMCs (MEC = 10 nM); induces proliferation of isolated mouse, rat, and dog splenocytes (EC50s = 3.98, 6.31, and 12.59 nM, respectively); inhibits BALF eosinophil infiltration in a rat model of ovalbumin-sensitized and -challenged allergic airway inflammation

Catalog No. 50-298-9067 Supplier Cayman Chemical Supplier No. 2945710 MG
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A TLR7 agonist (EC50 = 50.1 nM in a reporter assay using HEK293 cells expressing the human receptor); selective for TLR7 over TLR8 (EC50 = >10 µM); induces IFN production in isolated human PBMCs (MEC = 10 nM); induces proliferation of isolated mouse, rat, and dog splenocytes (EC50s = 3.98, 6.31, and 12.59 nM, respectively); inhibits BALF eosinophil infiltration in a rat model of ovalbumin-sensitized and -challenged allergic airway inflammation

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