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Cayman Chemical SNX-2112, Purity: ≥98%, CAS: 908112-43-6, 10 mg
SDP

Catalog No. 502987970
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A potent Hsp90 inhibitor (Kd = 30 nM); induces down-regulation of client proteins HER2 and Akt in vitro; inhibits proliferation in a panel of cancer cell lines (IC50s = 10-50 nM); inhibits tumor growth in a BT474 breast cancer mouse xenograft model; active metabolite of the prodrug SNX-5542 and preferentially accumulates in tumor tissue of mice treated with a single oral dose of 75 mg/kg SNX-5542

Catalog No. 50-298-7970 Supplier Cayman Chemical Supplier No. 2235910 MG
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A potent Hsp90 inhibitor (Kd = 30 nM); induces down-regulation of client proteins HER2 and Akt in vitro; inhibits proliferation in a panel of cancer cell lines (IC50s = 10-50 nM); inhibits tumor growth in a BT474 breast cancer mouse xenograft model; active metabolite of the prodrug SNX-5542 and preferentially accumulates in tumor tissue of mice treated with a single oral dose of 75 mg/kg SNX-5542

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