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Cayman Chemical ANTIBODY SpInorphIn 500ug

Supplier: Cayman Chemical 29914500 UG

An agonist of the adenosine A2A receptor and an inhibitor of ENT1 (Kis 4 39 and 3 47 UM for the human receptor and guinea pig transporter respectively) decreases adenosine uptake by 80 in PC12 cells at 61 UM and increases brain levels of adenosine in a transgenic mouse model of Huntingtons disease at 20 mg/kg rescues motor performance and increases survival in a transgenic mouse model of Huntingtons disease at 0 11 mg/kg
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