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Cayman Chemical SZL P1-41, Purity: ≥98%, CAS: 222716-34-9, 5 mg
SDP

Catalog No. 502936748
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An inhibitor of Skp2; inhibits the interaction between Skp2 and Skp1 to block Skp2 E3 ubiquitin ligase activity at 5 μM; inhibits Skp2 over Fbw7 and β-TrCP E3 ubiquitin ligase activity in HEK293T cells; reduces survival of LNCaP and PC3 prostate cancer cells via inhibition of aerobic glycolysis and induction of apoptosis; reduces tumor volume in A549 lung cancer and PC3 prostate cancer mouse xenograft models at 40 and 80 mg/kg

Catalog No. 50-293-6748 Supplier Cayman Chemical Supplier No. 261425 MG
May include imposed supplier surcharges.
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An inhibitor of Skp2; inhibits the interaction between Skp2 and Skp1 to block Skp2 E3 ubiquitin ligase activity at 5 μM; inhibits Skp2 over Fbw7 and β-TrCP E3 ubiquitin ligase activity in HEK293T cells; reduces survival of LNCaP and PC3 prostate cancer cells via inhibition of aerobic glycolysis and induction of apoptosis; reduces tumor volume in A549 lung cancer and PC3 prostate cancer mouse xenograft models at 40 and 80 mg/kg

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