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Cayman Chemical ANTIBODY TC-E 5002 1mg

Supplier: Cayman Chemical 177171 MG
A KDM2/7 inhibitor (IC50s = 6.8, 0.2, and 1.2 µM for KDM2A, KDM7A, and KDM7B, respectively); selective for the KDM2/7 subfamily over KDM4A, KDM4C, KDM5A, and KDM6A/UTX (IC50s = >120, 83, 55, and 100 µM, respectively); inhibits growth of N2a, KYSE150, and HeLa cells (GI50s = 86, 16, and 40 µM, respectively); increases H3K27me2 levels, decreases gene expression of E2F1, and leads to cell cycle arrest in the G0/G1 phase in vitro
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