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Cayman Chemical TM5275, Purity: ≥95%, CAS: 1103926-82-4, 25 mg
SDP

Catalog No. 502995573
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A PAI-1 inhibitor (IC50 = 6.95 µM); inhibits formation of a complex consisting of tPA, PAI-1, and GFP on VECsin vitro, prolonging the time that tPA is retained on VECs; decreases blood clot weight in a rat model of arteriovenous shunt thrombosis when used at doses of 10 and 50 mg/kg; increases the time to primary occlusion in a ferric chloride-treated carotid artery thrombosis model in rats when used at doses of 1 and 3 mg/kg; increases the time to primary occlusion in a cynomolgus monkey model of photochemical-induced arterial thrombosis when used at a dose of 10 mg/kg; does not affect platelet activity, activated partial thromboplastin time, prothrombin time, or prolong bleeding time

Catalog No. 50-299-5573 Supplier Cayman Chemical Supplier No. 2315125 MG
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A PAI-1 inhibitor (IC50 = 6.95 µM); inhibits formation of a complex consisting of tPA, PAI-1, and GFP on VECsin vitro, prolonging the time that tPA is retained on VECs; decreases blood clot weight in a rat model of arteriovenous shunt thrombosis when used at doses of 10 and 50 mg/kg; increases the time to primary occlusion in a ferric chloride-treated carotid artery thrombosis model in rats when used at doses of 1 and 3 mg/kg; increases the time to primary occlusion in a cynomolgus monkey model of photochemical-induced arterial thrombosis when used at a dose of 10 mg/kg; does not affect platelet activity, activated partial thromboplastin time, prothrombin time, or prolong bleeding time

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