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Cayman Chemical TRO 19622, Purity: ≥95% (mixture of isomers), CAS: 22033-87-0, 100 mg
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Catalog No. 502981455
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A mitochondrial-targeted neuroprotective agent; binds to and inhibits mPTP opening; prevents arachidonic acid-induced mPTP opening in HeLa cells at 10 µM; promotes survival of motor neurons in vitro in the absence of neurotrophic factors (EC50 = 3.2 µM); promotes survival of motor neurons in vivo in a neonatal rat model of facial nerve axotomy at 100 mg/kg per day; delays onset of motor deficits and extends survival in the SOD1G93A transgenic model of ALS; increases the latency to paw withdrawal in a mechanical hyperalgesia test in rat models of streptozotocin-induced diabetic and vincristine-induced neuropathic pain at 30 and 100 mg/kg

Catalog No. 50-298-1455 Supplier Cayman Chemical Supplier No. 21264100 MG
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A mitochondrial-targeted neuroprotective agent; binds to and inhibits mPTP opening; prevents arachidonic acid-induced mPTP opening in HeLa cells at 10 µM; promotes survival of motor neurons in vitro in the absence of neurotrophic factors (EC50 = 3.2 µM); promotes survival of motor neurons in vivo in a neonatal rat model of facial nerve axotomy at 100 mg/kg per day; delays onset of motor deficits and extends survival in the SOD1G93A transgenic model of ALS; increases the latency to paw withdrawal in a mechanical hyperalgesia test in rat models of streptozotocin-induced diabetic and vincristine-induced neuropathic pain at 30 and 100 mg/kg

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