Cayman Chemical ANTIBODY UCM53 500ug

Supplier:  Cayman Chemical 21768500 UG

An inhibitor of bacterial cell division; binds to the GTP site of the cell division protein FtsZ from B. subtilis in a fluorescent anisotropy assay; reduces the number of FtsZ rings and increases the number of foci in B. subtilis at 3 μM and induces filamentation at 12 μM; active against laboratory strains and clinical isolates of the Gram-positive bacteria B. subtilis, S. aureus, E. faecium, and E. faecalis (MICs = 2-8 mg/L) but is less effective against S. pneumoniae and the Gram-negative bacteria P. aeruginosa, E. coli, and K. pneumoniae (MICs = 32-128 mg/L); inhibits cell growth in a panel of cancerous (IC50s = 16.9-76.5 mg/L) and non-cancerous mammalian cell lines (IC50s = 23.5-93.9 mg/L)

Catalog No. 50-298-5852