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Cayman Chemical UM-164, Purity: ≥98%, CAS: 903564-48-7, 10 mg
SDP

Catalog No. 502935162
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An inhibitor of Src and p38 MAPK kinases (Kds = 2.7, 2.2, and 5.5 nM for c-Src, p38α, and p38β, respectively); also inhibits Fyn, Yes, Lyn, Abl, Arg, Ack, Csk, EphB2, EphB4, and Zak at 500 nM; inhibits cell growth in a panel of TNBC cell lines (IC50s = 6.1-260 nM) and in a patient-derived TNBC cell line (IC50 = 320 nM); induces cell cycle arrest at the G1/S phase MDA-MB-231 and SUM149 cells at 1 μM; inhibits cell motility and invasion in MDA-MB-231 and SUM149 cells at ≥ 50 nM; reduces tumor growth in SUM149 and MDA-MB-231 mouse xenograft models at ≥10 mg/kg

Catalog No. 50-293-5162 Supplier Cayman Chemical Supplier No. 2618810 MG
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An inhibitor of Src and p38 MAPK kinases (Kds = 2.7, 2.2, and 5.5 nM for c-Src, p38α, and p38β, respectively); also inhibits Fyn, Yes, Lyn, Abl, Arg, Ack, Csk, EphB2, EphB4, and Zak at 500 nM; inhibits cell growth in a panel of TNBC cell lines (IC50s = 6.1-260 nM) and in a patient-derived TNBC cell line (IC50 = 320 nM); induces cell cycle arrest at the G1/S phase MDA-MB-231 and SUM149 cells at 1 μM; inhibits cell motility and invasion in MDA-MB-231 and SUM149 cells at ≥ 50 nM; reduces tumor growth in SUM149 and MDA-MB-231 mouse xenograft models at ≥10 mg/kg

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