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Cayman Chemical ANTIBODY ZD 4190 50mg
SDP

Catalog No. 502944032
Encompass_Preferred

A VEGFR1, VEGFR2, and EGFR inhibitor (IC50s = 0.7, 0.03, and 0.4 µM, respectively); selective for these kinases over PDGFRβ, FGFR1, and HER2 (IC50s = 3.4, >100, and >100 µM, respectively) and MEK, Cdk2, IGF-1R, Akt, and Tie2 (IC50s = >10, >10, >20, >20, and >100 µM, respectively); selectively inhibits VEGF- or EGF-induced proliferation of HUVECs over FGF-induced proliferation of HUVECs (IC50s = 0.05, 0.05, and 1.5 µM, respectively); reduces tumor volume in a Calu-6 NSCLC mouse xenograft model at 100 mg/kg; inhibits training-induced increases in collateral blood flow and white gastrocnemius muscle capillarity in exercise-trained rats

Catalog No. 50-294-4032 Supplier Cayman Chemical Supplier No. 4224850 MG
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A VEGFR1, VEGFR2, and EGFR inhibitor (IC50s = 0.7, 0.03, and 0.4 µM, respectively); selective for these kinases over PDGFRβ, FGFR1, and HER2 (IC50s = 3.4, >100, and >100 µM, respectively) and MEK, Cdk2, IGF-1R, Akt, and Tie2 (IC50s = >10, >10, >20, >20, and >100 µM, respectively); selectively inhibits VEGF- or EGF-induced proliferation of HUVECs over FGF-induced proliferation of HUVECs (IC50s = 0.05, 0.05, and 1.5 µM, respectively); reduces tumor volume in a Calu-6 NSCLC mouse xenograft model at 100 mg/kg; inhibits training-induced increases in collateral blood flow and white gastrocnemius muscle capillarity in exercise-trained rats

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