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Cayman Chemical ZLY032, Purity: ≥98%, CAS: 2314465-67-1, 5 mg
SDP

Catalog No. 502991910
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A dual agonist of FFAR1/GPR40 (EC50 = 68 nM in a FLIPR assay) and PPARδ (102 nM in a reporter assay); selective for FFAR1 and PPARδ over PPARα and PPARγ (EC50s = >10 µM for both); reduces blood glucose levels in an oral glucose tolerance test and decreases plasma total cholesterol and triglyceride levels in the ob/ob mouse model of metabolic disease at 40 mg/kg; reduces hepatic steatosis and plasma ALT and AST levels in a mouse model of non-alcoholic steatohepatitis (NASH) induced by a methionine and choline-deficient diet at 40 mg/kg

Catalog No. 50-299-1910 Supplier Cayman Chemical Supplier No. 314855 MG
May include imposed supplier surcharges.
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A dual agonist of FFAR1/GPR40 (EC50 = 68 nM in a FLIPR assay) and PPARδ (102 nM in a reporter assay); selective for FFAR1 and PPARδ over PPARα and PPARγ (EC50s = >10 µM for both); reduces blood glucose levels in an oral glucose tolerance test and decreases plasma total cholesterol and triglyceride levels in the ob/ob mouse model of metabolic disease at 40 mg/kg; reduces hepatic steatosis and plasma ALT and AST levels in a mouse model of non-alcoholic steatohepatitis (NASH) induced by a methionine and choline-deficient diet at 40 mg/kg

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