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Medchemexpress LLC Antitumor agent-127 | 3034861-58-7 | 99.09% | 1670.92 | 5 MG
Supplier: Medchemexpress LLC HY1610965MG
Antitumor agent-127 (compound 1) is a parent macrocyclic peptide that displays nanomolar cell-based binding to ROR1 and relatively good internalization in 786-O and MDA-MB-231 tumor cell lines. It does not induce apoptosis in Mia PaCa-2 cells, a model pancreatic tumor cell line with low cell surface expression of ROR1.
- Displays nanomolar cell-based binding to ROR1.
- Demonstrates good internalization in 786-O and MDA-MB-231 tumor cell lines.
- Does not induce apoptosis in Mia PaCa-2 cells.
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