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TARGETMOL CHEMICALS INC AP 18 5MG
Supplier: TARGETMOL CHEMICALS INC T215435MG
Also available in 1mg 2mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1 respectively. AP-18 could reverse complete Freund's adjuvant (CFA)-induced mechanical hyperalgesia in mice. AP-18 could attenuate Yo-Pro uptake induced by 30 μM AITC in a concentration-dependent manner (IC50= 10.3 μM). purity: 99%
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