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ABclonal Technology AP0068-1000ul Phospho-MAP2K4-S
Supplier: ABclonal Technology AP00681000UL
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development They form a three-tiered signaling module composed of MAPKKKs MAPKKs and MAPKs This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues A similar protein in mouse has been reported to play a role in liver organogenesis A pseudogene of this gene is located on the long arm of chromosome X Alternative splicing results in multiple transcript variants
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